Related Questions

High deductible. Limited coverage of outpatient care. Would really help to know what tests, evaluations are required to diagnose chronic myelogenous leukemia and follow it after treatment.?

Nccn.org. Awful predicament. CML is one of the success stories with the new therapies, but proper follow up is important to assure optimal long term survival on the new oral agents. There are good patient assistance programs to assist with your medications. Review the web address above and CML page with your doc to plan the needed tests. Read more...

What sort of disease is chronic myelogenous leukemia (c.M.L.)?

Bcr-abl. CML is a clonal disorder (cancer) of the white blood cells in the blood (= -emia part). Other leukemias include cll, aml, all, etc. CML is often diagnosed by testing on peripheral blood or bone marrow. The bcr-abl translocation (philadelphia chromosome) is found in cml. Treatment may be a variety of pills. The most common initial treatment has been gleevec (imatinib). Other drugs are available. Read more...

What is chronic myelogenous leukemia?

A blood cancer. CML is a blood cancer that develops slowly (hence chronic). If untreated it will eventually be life threatening. It is associated a unique chromosomal injury, the philadelphia chromosome. New drugs (tkis) target this damage and reliably produce remissions in early stage patients that often are long lasting. Read more...
See below... Chronic myelogenous leukemia (CML) is a type of leukemia, which is a type of blood cancer. Like other chronic leukemias, CML is not particularly aggressive and can be successfully treated in most patients. Read more...

Dangers of chronic myelogenous leukemia?

Can be fatal. This is a disease that was associated with a shortened life span. The discovery of a specific cancer cell mutation and medications that attack that mutation have dramatically affected the outcome. This is now a disease that people can live for many years and be functional and productive. Read more...

What is chronic myelogenous leukemia (cml)?

White cell cancer. The bone marrow cells that produce granulocytes (needed to fight infections) grow out of control and are present in large numbers in the blood and other organs. The disease is quite treatable these days because of targeted therapy and long lasting remissions are possible in most people. Read more...
Chronic leukemia. CML is a type of chronic leukemia that is associated with a specific genetic change called the philadelphia chromosome. This genetic change in the cancer cells is targeted by a type of oral chemotherapy drug called a tyrosine kinase inhibitor. CML usually responds very well to these drugs although it is not cured with the pills. A stem cell transplant can be used in resistant cases. Read more...

How should I treat chronic myelogenous leukemia?

CML. CML is associated with philadelphia chromosome that result in the abnormal bcr-abl fusion gene. This becomes the target of treatment in cml. Oral tyrosine kinase inhibitor (tki) is the treatment of cml. The 1st generation is gleevec. Other tki that is more specific to block the bcr/abl fusion gene also available- sprycel and tasigna (nilotinib). Bone marrow transplant is available only for specific case. Read more...
By oncologist. This is a somewhat indolent form of leukemia which responds to treatment and can be carried for many years without major illenss. You could only have known about this if you had a bone marrow and blood test from your oncologist whose recommendations i would continue to follow. Read more...
See below... First of all, the treatment for any type of leukemia should be coordinated by a hematologist/oncologist. To answer your question, chemotherapy is usually necessary like for any other type of leukemia; however, there is also a special drug that is central in the chronic treatment of cml, namely Gleevec (imatinib), with a specific benefit in this type of leukemia. Read more...

What kind of disorder is chronic myelogenous leukemia?

Myeloproliferative. It is in a group of disorders referred to as myeloproliferative neoplasms. There are essentially four: chronic myelogenous leukemia, essential thrombocytosis, polycythemia rubra vera and myelofibrosis. Hope this helps. Read more...

What are different ways to treat chronic myelogenous leukemia?

CML. CML is associated with philadelphia chromosome that result in the abnormal bcr-abl fusion gene. This becomes the target of treatment in cml. Oral tyrosine kinase inhibitor (tki) is the treatment of cml. The 1st generation is gleevec. Other tki that is more specific to block the bcr/abl fusion gene also available- sprycel and tasigna (nilotinib). Bone marrow transplant is available only for specific case. Read more...
Medications. The initial treatment for CML is with oral medications called tyrosine kinase inhibitors. For recurrent disease, other chemotherapy drugs or a stem cell transplant may be used. Read more...