3 doctors weighed in:

ANA was 1:320, nuclear coarse speckled. Anti-RNP 1.3. Likely scleroderma or MCTD or lupus? Only chest pain and mild acid reflux. 28 female.

3 doctors weighed in
Dr. Cynthia Archer
Internal Medicine
2 doctors agree

In brief: The diagnosis of

Connective tissue disorders is tricky and mainly clinical.
Antibodies help in the classification but lupus, scleroderma and MCTD are all diseases with a spectrum of clinical manifestations. Many people meet criteria for more than one autoimmune disease. Treatment typically involves biological agents, steroids, and other immunosuppressants. Ask your rheumatologist what your specific diagnosis is.

In brief: The diagnosis of

Connective tissue disorders is tricky and mainly clinical.
Antibodies help in the classification but lupus, scleroderma and MCTD are all diseases with a spectrum of clinical manifestations. Many people meet criteria for more than one autoimmune disease. Treatment typically involves biological agents, steroids, and other immunosuppressants. Ask your rheumatologist what your specific diagnosis is.
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