Bro taking zyvox, (linezolid) now has mouth sores and possible hemorrhoids. He informed the doc but nothing was done. Is this a normal side effect of the drug?

See full answer. While Zyvox (linezolid) can cause oral thrush & tongue discoloration, I didn't find any direct link to hemorrhoids. Since it is an antibiotic, though, it can cause diarrhea, and straining with diarrhea can cause hemorrhoids.