What are tests, treatment for cholestasis of pregnancy?

Med, early delivery. Intrahepatic cholestasis is usually first noticed when a pregnant woman complains of itching all over the body but no rash. Testing will show abnormal bile salt levels and liver function tests. There is a medication that relieves the itching and lowers bile salt, but there is increased risk for stillbirth, so close monitoring of the pregnancy and delivery as soon as feasible is usual management.

Related Questions

I had cholestasis of pregnancy. I am over 2mo post delivery and the itching hasn't gone away. Liver function tests are normal. What do I do now?

Specialist . The itching from cholestasis should resolve 24-48 hrs after delivery. If you are still itching then it is from something else. Schedule a visit with an allergy/immunology specialist or perhaps a dermatologist. Read more...

What is the result of liver function tests in intrahepatic cholestasis of pregnancy?

Cholestasis. You could elevated bilirrubin and alkaline phosphatase predominantly. Others sucn as transaminases can be elevated too. They will all normalize upon delivery. Read more...

Are any special tests needed, or can a regular obgyn doctor see me for my intrahepatic cholestasis of pregnancy?

Cholestasis of preg. See your OB and he will get help if he needs a specialist. Read more...
Fetal monitoring. These pregnancies need to be followed closely since cholestasis of pregnancy is associated with fetal compromise including stillbirth. Serial liver tests & bile acids are checked; non-stress test are recommended 2x/week, and treatment (actigall (ursodiol) 300mg 2x/day) often is beneficial. An OB should be able to manage your care, some refer to mfm. Either should deliver you by 37 weeks if all else is well. Read more...

Which treatment works the best and fastest for intrahepatic cholestasis of pregnancy?

See your doc. The one we know it works in relieving the symptoms if itching is the ursodeoxycolic acid. But in pregnancy this is a very serious condition that requires frequent fetal monitoring, maternal monitoring and potentially delivery before your due date. Please see and ob/gyn specialized in high risk pregnancy if you dont have one. Read more...

What meds are good for cholestasis of pregnancy? I had it once and don't want to experience it again.

UCDA. Ursodeoxycholic acid (udca) is used in the treatment of intrahepatic cholestasis of pregnancy (icp). We don't know exactly how udca works, but we think it improves bile salt loss from the liver into the bile, which reduces serum bile acid, liver enzyme, and bilirubin levels. This reduces itching, and the risk to the fetus/mother, allowing deliver closer to term. Udca is safe to use in pregnancy. Read more...
Cholestyramine. Urso (udca) is one medication; another is cholestyramine. To summarize, you should suspect cholestasis of pregnancy when there is intense itching and no corresponding rash on the skin. Lab tests should be ordered to confirm abnormal liver function. Consequences of cholestasis include fetal death, premature labor and postpartum hemorrhage--all requiring close monitoring. Read more...

How is cholestasis of pregnancy diagnosed?

History/Physical/Lab. Cholestasis is diagnosed by doing a complete medical history, physical examination, and blood tests that evaluate liver function, bile acids, and bilirubin. Additionally, an ultrasound can de done to rule out gall bladder stones causing blockage. 1-2 preg/1000 is affected by cholestasis of pregnancy. It may be related to adverse pregnancy events like preterm labor, or at worse, stillbirth. Read more...
Bile Acid levels. Cholestasis of pregnancy presents with total body itching, usually no rash, & diagnosis is usually made with an elevated level of bile acids. We also follow liver functions, treat with ursodiol (actigall) & monitor the fetus with twice weekly nsts & afi checks. Early delivery is usually warranted to avoid demise, no one really has a good explanation why this occurs. Take care. Read more...