5 doctors weighed in:
Test for syphilis - what do RPR reac and vdrl reac mean?
5 doctors weighed in

Dr. Joseph Woods
Pathology
2 doctors agree
In brief: Screening tests.
Vdrl (venerial disease research laboratory) tests against anti-cardiolipin antibodies and RPR (papid plasma reagin) tests against nonspecific antibodies suggestive of syphilis and are screening tests.
Treponemal antibody tests, like fta-abs and mha-tp usually become positive two to five weeks after the initial infection. These are used to confirm syphilis and stay positive, even after therapy.

In brief: Screening tests.
Vdrl (venerial disease research laboratory) tests against anti-cardiolipin antibodies and RPR (papid plasma reagin) tests against nonspecific antibodies suggestive of syphilis and are screening tests.
Treponemal antibody tests, like fta-abs and mha-tp usually become positive two to five weeks after the initial infection. These are used to confirm syphilis and stay positive, even after therapy.
Dr. Joseph Woods
Dr. Joseph Woods
Thank
Dr. Ed Friedlander
Pathology
1 doctor agrees
In brief: Positive tests
You may want to follow them up with more specific tests, or your physician may simply treat depending on history.

In brief: Positive tests
You may want to follow them up with more specific tests, or your physician may simply treat depending on history.
Dr. Ed Friedlander
Dr. Ed Friedlander
Thank
Get help from a real doctor now
Dr. Adam Levy
Board Certified, Obstetrics & Gynecology
33 years in practice
1M people helped
Continue
108,000 doctors available
Read more answers from doctors