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Is breast cancer caused by a mutation in the gene or by a problem with the gene expression?

1 doctor weighed in
Dr. Myron Arlen
Surgery - Oncology

In brief: Gene mutation

If not a genetically inherited , environmental conditions initiate the induction of the breast lesion.
The most common mutation occurs with the long terminal repeat of the MMTV virus enters the Wnt-1 gene. This produces an over expression of B-catenin which results in transformation. EBV infection probably needed for FGARAT production that acts to overexpress telomerase inducing immortality.

In brief: Gene mutation

If not a genetically inherited , environmental conditions initiate the induction of the breast lesion.
The most common mutation occurs with the long terminal repeat of the MMTV virus enters the Wnt-1 gene. This produces an over expression of B-catenin which results in transformation. EBV infection probably needed for FGARAT production that acts to overexpress telomerase inducing immortality.
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