14 doctors weighed in:

Is ertapenem or zosyn (piperacillin and tazobactam) better for diabetic ulcer foot infections?

14 doctors weighed in
Dr. Luis Villaplana
Internal Medicine
7 doctors agree

In brief: IT ALL DEPENDS ON

Which bacteria is causing the infection.

In brief: IT ALL DEPENDS ON

Which bacteria is causing the infection.
Dr. Luis Villaplana
Dr. Luis Villaplana
Thank
1 comment
Dr. Latisha Smith
Also if the foot infection is associated with infection of the underlying bone sometimes double antibiotic coverage is prescribed as bone infection can lead to loss of limb if not cured.
Dr. Payam Rafat
Podiatry
4 doctors agree

In brief: It depends

Both zosyn (piperacillin and tazobactam) ertapenem are very powerful antibiotic which are generally very effective for diabetic foot ulcers.
One must however know which organism we are dealing with in order to determine the best choice of antibiotic. Antibiotic selection should be selected based on a culture and sensitivity.

In brief: It depends

Both zosyn (piperacillin and tazobactam) ertapenem are very powerful antibiotic which are generally very effective for diabetic foot ulcers.
One must however know which organism we are dealing with in order to determine the best choice of antibiotic. Antibiotic selection should be selected based on a culture and sensitivity.
Dr. Payam Rafat
Dr. Payam Rafat
Thank
Dr. Michael Ein
Internal Medicine - Infectious Disease
2 doctors agree

In brief: Equal

Both would be appropriate treatment.
Zosyn (piperacillin and tazobactam) would cover most strains of pseudomonas and enterococcus while ertapenem would be better if esbl producing bacteria were involved. Neither drug covers MRSA so vancomycin is usually included in empirical therapy of these infection. De-escalation and definitive therapy is determined by deep tissue or wound culture results.

In brief: Equal

Both would be appropriate treatment.
Zosyn (piperacillin and tazobactam) would cover most strains of pseudomonas and enterococcus while ertapenem would be better if esbl producing bacteria were involved. Neither drug covers MRSA so vancomycin is usually included in empirical therapy of these infection. De-escalation and definitive therapy is determined by deep tissue or wound culture results.
Dr. Michael Ein
Dr. Michael Ein
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Dr. David Hardin
Wound care
1 doctor agrees

In brief: Neither

If indeed you have an infection a proper culture should be done and the choice of antibiotic based on results.

In brief: Neither

If indeed you have an infection a proper culture should be done and the choice of antibiotic based on results.
Dr. David Hardin
Dr. David Hardin
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