14 doctors weighed in:
Is ertapenem or zosyn (piperacillin and tazobactam) better for diabetic ulcer foot infections?
14 doctors weighed in

Dr. Luis Villaplana
Internal Medicine
7 doctors agree
In brief: IT ALL DEPENDS ON
Which bacteria is causing the infection.

In brief: IT ALL DEPENDS ON
Which bacteria is causing the infection.
Dr. Luis Villaplana
Dr. Luis Villaplana
Thank
1 comment
Dr. Latisha Smith
Also if the foot infection is associated with infection of the underlying bone sometimes double antibiotic coverage is prescribed as bone infection can lead to loss of limb if not cured.
Dr. Payam Rafat
Podiatry
4 doctors agree
In brief: It depends
Both zosyn (piperacillin and tazobactam) ertapenem are very powerful antibiotic which are generally very effective for diabetic foot ulcers.
One must however know which organism we are dealing with in order to determine the best choice of antibiotic. Antibiotic selection should be selected based on a culture and sensitivity.

In brief: It depends
Both zosyn (piperacillin and tazobactam) ertapenem are very powerful antibiotic which are generally very effective for diabetic foot ulcers.
One must however know which organism we are dealing with in order to determine the best choice of antibiotic. Antibiotic selection should be selected based on a culture and sensitivity.
Dr. Payam Rafat
Dr. Payam Rafat
Thank
Dr. Michael Ein
Internal Medicine - Infectious Disease
2 doctors agree
In brief: Equal
Both would be appropriate treatment.
Zosyn (piperacillin and tazobactam) would cover most strains of pseudomonas and enterococcus while ertapenem would be better if esbl producing bacteria were involved. Neither drug covers MRSA so vancomycin is usually included in empirical therapy of these infection. De-escalation and definitive therapy is determined by deep tissue or wound culture results.

In brief: Equal
Both would be appropriate treatment.
Zosyn (piperacillin and tazobactam) would cover most strains of pseudomonas and enterococcus while ertapenem would be better if esbl producing bacteria were involved. Neither drug covers MRSA so vancomycin is usually included in empirical therapy of these infection. De-escalation and definitive therapy is determined by deep tissue or wound culture results.
Dr. Michael Ein
Dr. Michael Ein
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Dr. David Hardin
Wound care
1 doctor agrees
In brief: Neither
If indeed you have an infection a proper culture should be done and the choice of antibiotic based on results.

In brief: Neither
If indeed you have an infection a proper culture should be done and the choice of antibiotic based on results.
Dr. David Hardin
Dr. David Hardin
Thank
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