Review this . http://www.nlm.nih.gov/medlineplus/ency/article/000414.htm.
High calcium in blod. The abnormally rapid process of bone remodelling that is associated with paget’s disease can sometimes lead to a build-up of calcium in the blood. The medical term for this is hypercalcaemia - leasds to extreme tiredness, depression, drowsiness, constipation , bone pain, heart failure, sarcoma is a type of cancer that starts in the bone cells. Very rarely it can occur as a complication of paget’s.