3 doctors weighed in:
What exactly are cox-1 and cox-2 inhibitors?
3 doctors weighed in

Dr. Rick Kirschner
General Practice
1 doctor agrees
In brief: Different
Cox-1 (cyclooxygenase-1) is an enzyme that regulates prostaglandins, and is important for a healthy stomach lining and kidneys.
Inhibition turns this off, leading to gastrointestinal bleeding. Cox-2 (cyclooxygenase-2) is an enzyme that makes the prostaglandins which increase inflammation, pain and fever. So a cox-2 inhibitor is, in effect, a pain blocker.

In brief: Different
Cox-1 (cyclooxygenase-1) is an enzyme that regulates prostaglandins, and is important for a healthy stomach lining and kidneys.
Inhibition turns this off, leading to gastrointestinal bleeding. Cox-2 (cyclooxygenase-2) is an enzyme that makes the prostaglandins which increase inflammation, pain and fever. So a cox-2 inhibitor is, in effect, a pain blocker.
Dr. Rick Kirschner
Dr. Rick Kirschner
Thank
Dr. Bruce Rothschild
Internal Medicine - Rheumatology
In brief: Anti-inflammatory dr
These are drugs that act on two types of enzymes; one which is associated with inflammatory arthritis (cox-2) and one which is important to protecting stomach from ulcers.

In brief: Anti-inflammatory dr
These are drugs that act on two types of enzymes; one which is associated with inflammatory arthritis (cox-2) and one which is important to protecting stomach from ulcers.
Dr. Bruce Rothschild
Dr. Bruce Rothschild
Thank
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