Does arthritis respond to medication or not?

Yes, but. There are various forms of arthritis and the treatment may be different depending on the form.
Yes. It may take trying several different medications but they can help arthritis.
Depends. There are different kinds of arthritis. Osteoarthritis is more common. Medications do not help the arthritis, but help manage the symptoms. In rheumatoid arthritis, there are medications that can help the arthritis and delay its progression. A rheumatologist is the best person to consult for this.