Yes. Do you need both chlortrimeton and benadryl (diphenhydramine)? It's better not to take Benadryl (diphenhydramine) on a regular basis.
Yes. Benadryl (diphenhydramine) has some potential to cause drowsiness in some people while zoloft usually does not. If needed, I feel you're taking Benadryl (diphenhydramine) while on zoloft should cause no problems. Your psychiatrist who is an expert in working with medications like zoloft would be best to answer this question, however.
Zoloft/Benadryl. Yes u can.