3 doctors weighed in:
Why are cu and ceruloplasmin levels paradoxically low in wilson's disease?
3 doctors weighed in

Dr. Ed Friedlander
Pathology
1 doctor agrees
In brief: Minor mystery
Copper is low because ceruloplasmin is low; most copper in the blood is carried on the protein.
Nobody really knows why ceruloplasmin tends to be low in Wilson's, and I hope that you also know that in about 30% of Wilson's patients it is not low at all, making is a very poor screening test.

In brief: Minor mystery
Copper is low because ceruloplasmin is low; most copper in the blood is carried on the protein.
Nobody really knows why ceruloplasmin tends to be low in Wilson's, and I hope that you also know that in about 30% of Wilson's patients it is not low at all, making is a very poor screening test.
Dr. Ed Friedlander
Dr. Ed Friedlander
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Dr. Martin Raff
Internal Medicine - Infectious Disease
1 doctor agrees
In brief: Hepatic storage
The hepatocytes in wilson's disease (hereditary in the ainu) store copper, removing it from the circulation.

In brief: Hepatic storage
The hepatocytes in wilson's disease (hereditary in the ainu) store copper, removing it from the circulation.
Dr. Martin Raff
Dr. Martin Raff
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