I have gained 20kgs since May after being put on mirtazipine for extreme depression. I take pregabalin for trigeminal neuralgia and use buprenorphine?

Pregabalin & weight. Pregabalin may cause you to have extra fluid or to gain weight. Although medication can cause weight gain, healthy habits can still help you mitigate the side effects and lose some weight. To stop weight gain caused by pregablin, you should drink lots of water, eat balanced meals and exercise routinely.