Liver was enlarged, recent ultrasound shows it has shrunk 2 cen. On prednisone and plaquenil-could that make it shrink? Would that cause right rib pain?

Diagnosis ? One can't really answer this question without knowing what the diagnosis of your large liver was. You been on prednisone and plaque will but you didn't say what you were looking for. The resize can decrease for other reasons too but we need to know what your liver biopsy showed hear what your physician told you your liver tissue. This is best discussed with your physician.