4 doctors weighed in:

My mother had an acoustic neuroma at 35 and was diagnosed with breast cancer at 55. Could this be related to li fraumeni syndrome?

4 doctors weighed in
Dr. Joseph Woods
Pathology
2 doctors agree

In brief: Some other disease.

This syndrome requires that the affected person meet 3 criteria - 1.
Patient had sarcoma <45 yrs., 2. 1st deg relative had any cancer <45., 3. Another 1st or 2nd deg. Relative had any cancer <45, or sarcoma at any age. Unless you or your mother had a sarcoma before 45 or another relative, like an aunt/grandparent had anything, this is not likely. But you/your mom should still get worked up.

In brief: Some other disease.

This syndrome requires that the affected person meet 3 criteria - 1.
Patient had sarcoma <45 yrs., 2. 1st deg relative had any cancer <45., 3. Another 1st or 2nd deg. Relative had any cancer <45, or sarcoma at any age. Unless you or your mother had a sarcoma before 45 or another relative, like an aunt/grandparent had anything, this is not likely. But you/your mom should still get worked up.
Dr. Joseph Woods
Dr. Joseph Woods
Thank
2 comments
Dr. Joseph Woods
It would be a good idea to go get worked up for some possible genetic mutation, like p53 which is seen in Li Fraumeni Syndrome, but also in other cancers. You also might find a strong family history link to the tumors your mother has, along with others.
Dr. Joseph Woods
Thanks! I hope your mom is OK now. Best of luck!
Dr. Richard Federbush
Internal Medicine
1 doctor agrees

In brief: Yes it is possible

This is a very rare genetic disorder in which predisposed individuals develope canxer at a young age and then develope a second.
The most common tumors involved are brain , breast, leukemias, sarcomas and adrenal carcinomas. Diagnosis requires specitic genetic testing.

In brief: Yes it is possible

This is a very rare genetic disorder in which predisposed individuals develope canxer at a young age and then develope a second.
The most common tumors involved are brain , breast, leukemias, sarcomas and adrenal carcinomas. Diagnosis requires specitic genetic testing.
Dr. Richard Federbush
Dr. Richard Federbush
Thank
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