I am 282 lbs. I have had pvc's in the past but not for a while now. I smoke. I want to know if I'm ok to start exercising regularly. Dr. Says im ok.?

Your doctor must . Have the info necessary to tell you to go ahead. I don't.
Your MD knows best. Your physician should know you the best regarding your medical condition and ability to proceed with an exercise program. You may consider working out with a partner or friend, or even a professional trainer if possible. This would diminish any startup anxiety on your part and may make exercising more fun, safe, and enjoyable.