I've got stills im 23, my joints r swollen I've been on prednisone high doses for months, I've had cort. Shots in knees, n ntfs don't work, what will help?

Other Rx. Even though tnfs did not help, there are other biologic agents which have shown good results. One drug is Kineret (anakinra) which works on il-1 ( interleukin-1) instead of tumor necrosis factor (tnf). Be sure to let your rheumatologist know that you are still in pain and that you cannot taper off the steroids.