Can I take buscopan with antihistimanes?

NOT recommended. Buscopan (hyoscine/scopolamine butylbromide, ) is a type of medicine called an antispasmodic (peripherally acting antimuscarinic-anticholinergic). It is used to relieve irritable bowel symptoms or 'abdominal cramps' . Buscopan can 'potentiate' (or increase) anti-cholinergic affects of anti-histamines so it not recommended to take at the same time.