How does deep brain stimulation (dbs) treat Parkinson's disease?

We don't fully know. But the wires are placed into deep basal ganglia nuclei and the electrical impulses stimulate the electrochemical discharges and basically help management of fluctuations and varying symptoms. One item of interest is absence of benefit if unresponsive to L-DOPA, so, obviously, this is one potential explanation, but not all to it.

Related Questions

What percentage of Parkinson's disease patients are good candidates for deep brain stimulation (DBS)?

Parkinson Diseases. DBS is typically reserved for patients with end stage type disease that failing medications. It is not a first line type of therapy. Read more...

Parkinson's disease - dbs deep brain stimulation, what does this do?

Electrical stim. This involves an exacting neurosurgical procedure and wire placement is critical, but the device can control tremors, imbalance, and on-off deterioration, and might remarkably transform capacity of advanced patients to function. Read more...

Is deep brain stimulation any help for Parkinson's disease?

Yes. The motor symptoms are often helped. Consider a consultation with an expert clinic specializing in this area. Not everyone is a candidate and all surgery has risks and benefits. Read more...
Yes, Absolutely!! Deep brain stimulation therapy of the stn (sub-thalamic nucleus) or gpi (globus pallidus interna) can greatly improve "on" time (good function with minimized symptoms) & greatly reduce dyskinesia (twisting, writhing, jerking movements during "on" time). Good candidates must be not demented, psychiatrically stable, & still demonstrating good symptom relief from meds, but with inconsistent results. Read more...

Is deep brain stimulation suggested for Parkinson's disease?

Yes. It is more successful than creating lesions within the brain. It is especially good in younger onset patients- yet can be placed in middle age patients. The location of the stimulation is what the neurosurgeon will determine to achieve the best benefit. Look for a specialist in functional neurosurgery. Read more...
Yes Class 1 evidence. There is high quality medical evidence for significant benefit from dbs in parkinson's disease. See this link: http://jama.Jamanetwork.Com/article.Aspx?Articleid=183161. Read more...

Can you tell me about deep brain stimulation for Parkinson's disease?

Hours of relief! Dbs is relatively a new intervention: surgically implanted electrical stimulator to a specific area in the brain, this procedure can bring hours of relief from symptoms of parkinson's. Its not a replacement for medications. This procedure is usually recommended when the patient's responsivity to drug treatment begins to decrease. Read more...

How effective is deep brain stimulation surgery for Parkinson's disease?

Parkinson's disease. Deep brain stimulation surgery has become an excellent adjunct treatment of Parkinson's disease but it is reserved for patients that have failed medical treatment and are continuing to worsen with their symptoms. Read more...

Gait freezingafter deep brain stimulation surgery for Parkinson's disease any suggestions?

Maximize CDS!! First, make sure your dbs programming is being done well by an experienced programmer. Get a second opinion if needed! then, make sure your regimen includes meds to maximize cds (continuous Dopamine stimulation), and thus maximally improve freezing. I call them grade "a" meds: a for Azilect & agonists (neupro (rotigotine) patch, Requip xl & Mirapex er). They last longer than sinemet or Comtan = less freezing! Read more...
Complex Issue. Gait is a very complex neurological function that relies on many systems functioning together. I would recommend that you see a specialist in dbs programming to help you maximize function. Read more...

If a person undergoes deep brain stimulation surgery for Parkinson's disease, are the tremors permanently cured?

Expect Improvement. Many patient experience a reduction in the tremors, but don't expect a "cure." sometimes medications can be decreased, and this can also provide overall improvement (less side effects). Read more...
DBS improves tremor . Parkinson's disease is a disease of the whole brain, and tremor is one sign. Luckily, dbs works great for tremor. It may even help the tremors permanently. However, dbs does not stop the progression of parkinson's disease. As the parkinson's disease progresses, other signs develop that are not helped by the dbs. This is a complex discussion that should be held with your movement disorders doc. Read more...

Could deep brain stimulation develop to become a cure for diseases such as alzheimer's and parkinson's?

Control measure. Dbs is not a cure currently and doubtful it will be a panacea. Yet, valuable when meds start failing in parkinson's but not yet in use for alzheimer's. Read more...
Watch for updates. Dbs for alzheimer's is a field with a lot of research being done. It is hard to predict what will be the outcome. There are some preliminary data from hopkins that shows promise. There is also a big initiative to study this further and there are formal clinical trials in the works. Read more...
No. DBS just modifies the neural circuitry to optimize the output of brain. It does not affect the genes or cells on a structural level. Cell based therapies in future could cure these diseases. Read more...