Flying w sickle cell
Yes it is. Like anyone else on the plane, if you're flying for long time, make sure you get up and move around.
For long trips, there is a risk of deep vein thrombosis
so the airline actually recommends you move your ankles in clockwise and then counterclockwise fashion. Like wax-on, wax-off for your feet. That was a karate
kid reference if you're a young person and never saw the classic film.
Answer assisted by Mahek Shah, Medical Student