Does anticardiolipin IgM (115ug/l) x 3 have any significance when it is rasied on its own? LA Positive but beta glycoprotein & other antibodies neg

Higher future risk. The cause of an elevated aCL without other diseases is unknown. That said, 50% of people with + lupus anticoagulant have or will have SLE. Presumably, manifestations require the aCL plus another problem - infection, one of a number of drugs, pregnancy, BC pills, etc. The significance is the higher than normal risk in the face of future immunological injury.