I'm having sharp pain in my right upper abdomen. What could be there?

RUQ ABD PAIN. First of all, it is important to distinguish pain that is emanating from the abdominal wall/muscles versus the intra-abdominal organs. If it is the latter, the gallbladder, liver, and colon are probably the top 3 organs responsible for pain in that area. Bottom line: as much as we would like to help, nothing can replace a face-to-face examination from a doctor to get to the bottom of this.