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What is pathophysiology of papillary thyroid cancer?

8 doctors weighed in
Dr. Ed Friedlander
Pathology
6 doctors agree

In brief: Like other cancers

Like all cancers, it results from accumulated genetic mutations that cause the cells to grow inappropriately and eventually destabilize the genome.
A variety of mutation groups are known. Most subtypes of papillary carcinoma of the thyroid are not especially aggressive and cures are usual.

In brief: Like other cancers

Like all cancers, it results from accumulated genetic mutations that cause the cells to grow inappropriately and eventually destabilize the genome.
A variety of mutation groups are known. Most subtypes of papillary carcinoma of the thyroid are not especially aggressive and cures are usual.
Dr. Ed Friedlander
Dr. Ed Friedlander
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Dr. John Yim
Surgery - Oncology

In brief: Multiple factors.

If by pathophysiology you mean cause of papillary thyroid cancer this has not been completely defined.
Undoubtedly there is a genetic component, that is what you are born with, but there is an environmental component as well. In particular, the association of radiation with papillary thyroid cancer has been found to be one of the clearest associations of an environmental factor with cancer.

In brief: Multiple factors.

If by pathophysiology you mean cause of papillary thyroid cancer this has not been completely defined.
Undoubtedly there is a genetic component, that is what you are born with, but there is an environmental component as well. In particular, the association of radiation with papillary thyroid cancer has been found to be one of the clearest associations of an environmental factor with cancer.
Dr. John Yim
Dr. John Yim
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