2 doctors weighed in:
If I took one imodium (loperamide) plus an hour ago can I take promethazine?
2 doctors weighed in

Dr. Ralph Morgan Lewis
Family Medicine
1 doctor agrees
In brief: Best not to
Imodium (loperamide) & Promethazine have an additive effect such that you risk severe constipation/paralytic ileus.
Give the Imodium (loperamide) time to work. Continue to replace fluids—water or beverage with electrolytes (sodium, potassium). If no improvement or if worse, see your doc for evaluation & treatment.

In brief: Best not to
Imodium (loperamide) & Promethazine have an additive effect such that you risk severe constipation/paralytic ileus.
Give the Imodium (loperamide) time to work. Continue to replace fluids—water or beverage with electrolytes (sodium, potassium). If no improvement or if worse, see your doc for evaluation & treatment.
Dr. Ralph Morgan Lewis
Dr. Ralph Morgan Lewis
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