Is it irregular for a 25 year old male to get a prostate exam?

Depends. It depends on the reason for the exam. Younger patients are less likely to have prostate difficulties, so in this regard it may be unusual. However, if the patient has a family history or symptomatic complaints that raise the physician's index of suspicion, a digital rectal exam may be performed. http://www.uspreventiveservicestaskforce.org/prostatecancerscreening.htm.