5 doctors weighed in:

What is her 2?

5 doctors weighed in
Dr. Sean Canale
Breast Surgery
4 doctors agree

In brief: Gene, marker

Her2 refers to a gene present in many normal cells that codes for a cell surface protein.
In 10-15% of breast cancers it is amplified (multiple copies producing a lot of the protein) which is associated with a more aggressive tumor. Herceptin (trastuzumab) (an antibody to the protein) reduces this aggressive nature. It's usually given with chemo for synergy.

In brief: Gene, marker

Her2 refers to a gene present in many normal cells that codes for a cell surface protein.
In 10-15% of breast cancers it is amplified (multiple copies producing a lot of the protein) which is associated with a more aggressive tumor. Herceptin (trastuzumab) (an antibody to the protein) reduces this aggressive nature. It's usually given with chemo for synergy.
Dr. Sean Canale
Dr. Sean Canale
Thank
Get help from a real doctor now
Dr. Jane Van Dis
Board Certified,
15 years in practice
47M people helped
Continue
108,000 doctors available
Read more answers from doctors