Is Tylenol (acetaminophen) with codeine safe for patients with Wolff Parkinson White Syndrome?

Yes. In general you should avoid drugs that affect conduction in the heart. Caffeine is also to be avoided as are alcohol, pseudephedrine (found in cold medicines) digoxin unless carefully monitored by your physician and smoking. Of course, avoid taking any recreational drugs. Tylenol with codeine taken as prescribed by a physician aware of your WPW should be safe.