2 doctors weighed in:

I have cellulitis. Taking Bactrim (sulfamethoxazole and trimethoprim) and Keflex. Is it necessary to take both? Do they cancel each other out?

2 doctors weighed in
Dr. Susan Arnoult
Family Medicine
1 doctor agrees

In brief: No

They don't cancel each other out.
There are times when we feel it is necessary to use 2 antibiotics from 2 different classes (such as Bactrim (sulfamethoxazole and trimethoprim) and Keflex) to cover the infection. I would continue both as your doctor prescribed.

In brief: No

They don't cancel each other out.
There are times when we feel it is necessary to use 2 antibiotics from 2 different classes (such as Bactrim (sulfamethoxazole and trimethoprim) and Keflex) to cover the infection. I would continue both as your doctor prescribed.
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