Can you die if you take five 75mg pills of Effexor (venlafaxine) for anxiety?

Take care. Taking too much effexor/venlafaxine can cause heart complications and if the overdose is severe, death can occur. However, the max dose of Effexor is 375 mg so five 75 mg tabs is the max dose. Do check in with your physician about this and take care to follow directions.