Related Questions

My mom has accidently taken three dasatinib tablets for her leukemia instead of two and is worried. What will happen?

Nothing serious. Taking one extra pill on one day would not make any difference as these drugs have been used at higher doses with minimal increase in toxicity but only when taken at higher dose continuously. But in her case with one extra dose, I do not expect any problems. So she can relax and forget about it. be careful in future. Read more...

What do you suggest if my grandmother has accidently taken three dasatinib tablets for her leukemia instead of two and is worried. Does anyone know what she should do?

CALL ONCOLOGIST. First of all call to inform her oncologist and get his opinion. Dasatinib (sprycel) dose is usually 100 mg daily, so I assume she has 50 mg tablets and was taking 2. It would be appropriate to hold tomorrow's dose and then resume treatment. Call her oncologist. . Read more...

Noticed there is a serious interaction between flomax, which I was just prescribed, and gleevec, but none with sprycel, (dasatinib) which I take for cml. Correct?

Increase serum Floma. Gleevec increases serum levels of flomax, and therefore dosage adjustment may be necessary. Flomax is metabolized through cyp3a4 and sprycel (dasatinib) is also a substrate for cyp3a4, so may also increase the levels of flomax. Read more...
The concern. Between Gleevec and Flomax, is that Gleevec inhibits a particular enzymes(cytochrome 3A4 and to a lesser extent 2D6) which metabolize Flomax. This can lead to higher levels of Flomax in your system and more at risk for associated adverse effects like low blood pressure and dizziness. Sprycel (dasatinib) inhibits 3A4 but much less than Gleevec so it should be less of an interaction/issue. Read more...

I felt my heart pulse in my head last night while I was watching TV. I have CML and started on Sprycel (dasatinib). Would that be the reason that happening?

It is a coincidence. If your heart is beating faster for any reasons, you may feel the heart beats in any part of the chest or head. This can happen with any emotional upheaval. I do not think that sprycel (dasatinib) has anything to do with it. Read more...

Usually average 1 cold per year. None since began taking Sprycel (dasatinib) for CML 4 years ago. Do these TKIs have antiviral properties?

Congratulations. Dasatinib, like imatinib tyrosine kinase inhibitors are great success in cancer treatment for CML etc.Suppressing abnormal white cells defective in combatting infections may have enhanced your body's normal white cells against colds,etc. These molecules block the TKI molecular switches on cells. They do not have antiviral properties. That said, side effects of TKIs include low blood count,takecare. Read more...

Sudden appearance of very dark blue vein on top of my foot. No pain but some mild tingling. No injury. I do tale dasatinib for cml and am 54.

No problem. This doesn't sound like a significant problem. If the vein gets hard and painful, it might be a phlebitis, but at that location would be low risk. Discuss with your physician if symptoms worsen. Read more...
Keep watch. I would not worry about it unless it does not go away in a few days or gets worse. There is a good Podiatrist in your area if you need it looked at. HVFA in Fishkill; Dr. David Kim. Read more...

CML 10/12. Gleevec. 5 log at 6 mths. Sprycel (dasatinib). 5 log at 6 mths. Stem cell transplant 4/14. 7/14 Blast crisis - 65% blast BM + Aspergillus F lung Help?

Difficult case. it is a complicated case obviously. first and foremost the infection has to be treated. i would suggest you to follow up with ID and oncologist very closely. importantly is to check if there is certain mutation like T315i mutation as this mutation is resistant to gleevec, sprycel, tasigna (nilotinib) - and should be treated with ponatinib or aurora kinase inhibitor etc. discuss with oncologist. God bless. Read more...