4 doctors weighed in:

What is hirschsprung disease and what are the major symptoms?

4 doctors weighed in
Dr. Troy Reyna
Surgery - Pediatric
2 doctors agree

In brief: Constipation

Hirschsprung's is being born with lack of certain nerves(nerves that cause relaxation) in the intestine.
When these nerves are missing the affected portion of the intestine/colon cannot relax, therefore obstruction results.

In brief: Constipation

Hirschsprung's is being born with lack of certain nerves(nerves that cause relaxation) in the intestine.
When these nerves are missing the affected portion of the intestine/colon cannot relax, therefore obstruction results.
Dr. Troy Reyna
Dr. Troy Reyna
Thank
Dr. Gerald Mandell
Nuclear Medicine

In brief: Lack ganglion cells

Hirschsprung’s disease (congenital megacolon) is caused by failed migration of colonic ganglion cells in utero.
Varying lengths of the distal colon are unable to relax, causing functional colonic obstruction.Can vary from very short segment to entire large bowel. Obstruction noted usually in infancy, Sometimes recognition is later due to intractable constipation.

In brief: Lack ganglion cells

Hirschsprung’s disease (congenital megacolon) is caused by failed migration of colonic ganglion cells in utero.
Varying lengths of the distal colon are unable to relax, causing functional colonic obstruction.Can vary from very short segment to entire large bowel. Obstruction noted usually in infancy, Sometimes recognition is later due to intractable constipation.
Dr. Gerald Mandell
Dr. Gerald Mandell
Thank
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