What is effect of questran (cholestyramine)?

Binding Bile Salts. Questran (cholestyramine) is a bile acid sequestrate to works by binding bile salts and cholesterol preventing their absorption in the GI tract. With decreased cholesterol absorption the liver makes more low density lipoprotein (ldl) receptors, which in turn decrease the number of LDL particles (ldl-p) in the blood. Additionally, Questran (cholestyramine) can cause increased triglyceride (tg) synthesis and higher blood tg levels.

Related Questions

What is questran (cholestyramine) used for?

Binding Bile Salts. Questran (cholestyramine) is a bile acid sequestrate that works by binding bile salts and cholesterol preventing their absorption in the GI tract. With decreased cholesterol absorption the liver makes more low density lipoprotein (ldl) receptors, decreasing the number of LDL particles (ldl-p) in the blood. However, Questran (cholestyramine) can cause increased triglyceride (tg) synthesis and higher blood tg levels. Read more...

Son had gallbladder out many years ago. He constantly has dumping syndrome still after everything he eats. Tried questran, correct eating. Any advice?

Insufficient info. Dumping syndrome usually occurs after gastric surgery, not gallbladder surgery. Vagal nerve damage is one cause, but your son needs an extensive evaluation by a gastroenterologist. He may not have dumping syndrome. you list his conditions to include vaginal dryness and hot flashes. ? Read more...

How effective is Cholestyramine (Questran) for treating atherosclerosis?

Very little effect. Basically it diminishes absorption of fat in the gut. Remember that only one third of your blood cholesterol is absorbed by the intestine and two thirds are made by your liver. You diminish cholesterol very little compared to statins (if they can be tolerated). There is no other known dramatic effect by which Questran (cholestyramine) treats atherosclerosis. Read more...

Are you prescribed questran (cholestyramine) for high cholesterol.?

Questran (cholestyramine) Questran (cholestyramine) can be used for management of high lipids. It is not usually a first line agent, but used in patients who are sensitive to statins or have elevated triglycerides that have not responded to statin therapy. It is usually added to another therapy. Read more...
Be careful. While Questran (cholestyramine) can be used to lower LDL (bad) cholesterol, it should not be used to lower trigylerices (fats in the blood). In fact, Questran (cholestyramine) may actually raise trigylerides. Best of luck! Read more...

When using questran (cholestyramine) do you have to be careful using antibiotics?

Yes - or any drug. Questran (cholestyramine) is a old medication for lowering cholesterol by binding bile salts in the intestine, and thereby removing cholesterol from the body. It also binds most medications, thereby preventing them getting into you to work. You should try to take Questran several hours away from any other medication. Read more...