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What cause the symptoms of sickle cell anemia?

2 doctors weighed in
Dr. Martin Raff
Internal Medicine - Infectious Disease
1 doctor agrees

In brief: Symptoms of SS

The altered shape of the red blood cells causes them to stack up together and clog blood vessels, depriving the tissues of adequate blood supply and oxygen.
The tissues then die (infarct) and this causes pain. The red cells also rupture or are eaten by the spleen and cause anemia. The spleen itself will gradually infarct, leaving the patient susceptible to infections.

In brief: Symptoms of SS

The altered shape of the red blood cells causes them to stack up together and clog blood vessels, depriving the tissues of adequate blood supply and oxygen.
The tissues then die (infarct) and this causes pain. The red cells also rupture or are eaten by the spleen and cause anemia. The spleen itself will gradually infarct, leaving the patient susceptible to infections.
Dr. Martin Raff
Dr. Martin Raff
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