Not usually. All medications have effects, which r what we prescribe them 4 nd side effects, which r everything else the med might do. Hopefully the effects outweigh the side effects. Aciphex (rabeprazole) is a ppi which prevents your stomach from making acid, which is one of the main function of the stomach. While controlling some symptoms, we don't know the long term effects yet of this yet. Protein maldigestion?