3 doctors weighed in:

Does the western blot trump the elisa? Tested positive via ELISA IgG for hsv2,but later tested negative via western blot. No symptoms. Do I have hsv2?

3 doctors weighed in
Dr. Gurmukh Singh
Pathology
2 doctors agree

In brief: Western blot more

specific, ELISA more sensitive.
One positive ELISA and one negative Western blot says that you do not have enough antibodies to HSV 2 for confirmation of diagnosis. It may be prudent to repeat the tests in 3-4 months to make sure that negative Western blot was not due to incomplete/early immune response.

In brief: Western blot more

specific, ELISA more sensitive.
One positive ELISA and one negative Western blot says that you do not have enough antibodies to HSV 2 for confirmation of diagnosis. It may be prudent to repeat the tests in 3-4 months to make sure that negative Western blot was not due to incomplete/early immune response.
Dr. Gurmukh Singh
Dr. Gurmukh Singh
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