Is schizophrenia a brain disease?

Brain Disease - Yes. We know that the symptoms of schizophrenia occur because of malfunctions in the brain. While the cause is unknown, the symptoms of schizophrenia has been thought to be a function of excess Dopamine new theories are beginning to emerge as to possible causes and as to the malfunctions of the brain leading to the symptoms of schizophrenia.
Yes . Schizophrenia's full cause and mechanisms are completely well known, but schizophrenia is a disorder of certain parts of the brain requiring treatments that target those parts.

Related Questions

What proof is there that schizophrenia is a detectable brain disease?

Schizophrenia. Neuro-imaging studies such as pet scans to detect brain changes on radiographs, and neuro-chemistry work to detect neurotransmitter abnormalities. Read more...
Clinical Exam. There is no neuroanatomical 'proof' of schizophrenia (though there is no such 'proof' that headaches exist either). There are some neuroanatomical correlates to schizophrenia (increased lateral ventricular size and corresponding decrease in gray matter), though such findings are not specific enough to be of diagnostic utility. The disease is detected through a comprehensive clinical assessment. Read more...
PET scans. There are pet scans that utilize special tracers for Dopamine receptors that show unique characteristics in schizophrenic patients. These scans are not necessary to make a clinical diagnosis of schizophrenia, but they confirm that schizophrenia is a "hardware" problem rather than a "software" problem. Read more...

What symptoms are different in schizophrenia and schizoaffective disorder? Is one a disease of the brain, other disorder?

Both brain disease. Both of these illnesses are "brain diseases, " and both have psychotic symptoms such as delusions, paranoia, hallucinations, thought disorder, etc. Schizoaffective patients also have mood dysregulation, but pure schizophrenics don't. Treatment for schizophrenia may be antipsychotics alone; schizoaffective people also need mood stabilizing agents. They may deal with mania & depression, + psychosis. Read more...