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Neonatal alloimune thrombocytopenia, what is this?

2 doctors weighed in
Dr. Jay Park
Pediatrics
1 doctor agrees

In brief: Low platelets count

Neonatal alloimmune thrombocytopenia occurs when fetal platelets contain an antigen inherited from the father that the mother lacks.
The mother forms antiplatelet antibodies against the this antigen; these cross the placenta and destroy fetal platelets, resulting in fetal and neonatal thrombocytopenia. Minority of affected newborns (about 20%) experiences severe bleeding including intracranial bl

In brief: Low platelets count

Neonatal alloimmune thrombocytopenia occurs when fetal platelets contain an antigen inherited from the father that the mother lacks.
The mother forms antiplatelet antibodies against the this antigen; these cross the placenta and destroy fetal platelets, resulting in fetal and neonatal thrombocytopenia. Minority of affected newborns (about 20%) experiences severe bleeding including intracranial bl
Dr. Jay Park
Dr. Jay Park
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