Probably will. Doxycycline is an antibiotic in the tetracycline family that is used often for spirochete illnesses, by far the most common today being lyme's disease. Often it is given preventively if there is clear exposure to a tick that got it's fangs into you and couldn't just be flicked off (this is appropriate). Don't take it with food, definitely not milk, and if mild side effect, stick with the course.
Hours to days to. .. Doryx (doxycycline) is a slow-release form of doxycyline, a tetracycline-type antibiotic. Common side effects include headache, nausea, acid stomach, joint pain, diarrhea, rash, yeast infections, menstrual cramps, skin discoloration, abnl kidney test. More serious side effects are also possible. The common side effects may start with the first dose; most will occur later; some can occur after months of use.