What are the long-term effects of shingles?

Pain most important. Even after shingles (or zoster) heals, the pain can be debilitating for months or years. This is why the vaccine for those over 60 is so important. There is a new clinical trial starting for cancer patients to receive an inactivated vaccine..They can not receive the current one because of their weakened immune system. Cancer patients are particularly susceptible to zoster.