3 doctors weighed in:

Any methotrexate side effects?

3 doctors weighed in
Dr. Thomas Namey
Internal Medicine - Rheumatology
2 doctors agree

In brief: Plenty : XX oral dos

Methotrexate is a surprisingly effective drug for many forms of arthritis and the consensus 1st choice for RA by the acr and eular (european).
The oral dosage is more problematic because of variable absorption and first-pass effect through liver. It is completely absorbed with sucutaneous injection and doesn't bolus liver. Hair loss can be a problem. Everyone should take 2mg of folic acid.

In brief: Plenty : XX oral dos

Methotrexate is a surprisingly effective drug for many forms of arthritis and the consensus 1st choice for RA by the acr and eular (european).
The oral dosage is more problematic because of variable absorption and first-pass effect through liver. It is completely absorbed with sucutaneous injection and doesn't bolus liver. Hair loss can be a problem. Everyone should take 2mg of folic acid.
Dr. Thomas Namey
Dr. Thomas Namey
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