What defect is responsible for hodgkin lymphoma?

Risk of Hodgkin's dz. There is no one "defect" that causes hodgkin's disease, but risk factors include a high socioeconomic status, having a family member with the disease, prior epstein-barr virus infection (mononucleosis), and immunosuppression as a result of conditions like aids, organ or marrow transplantation, autoimmune disease, and immunosuppressant medications.
Hodgkin's lymphoma. is a malignancy of a type of B-lymphocytes, known as a Hodgkin and Reed-Sternberg cell (HRS). It has been a challenge to study this disease because the HRS cell secretes factors that causes it to be surrounded by large numbers of normal lymphocytes. LRS cell neoplasia appears to result from a combination of gene mutations, like other lymphomas; and are often infected with EBV (Epstein Barr virus).

Related Questions

Can a teen have hodgkin lymphoma?

Teenage is a. Common time for hodgkin's disease. Can be an easy to notice lymph node, neck or arm pit, but might be a hard to notice liver, spleen or mediastinal mass associated with sweats, fever, weight loss (b symptoms). Read more...
Yes. Cancers in teenagers are rare, but hodgkin lymphoma does happen in this population. It is curable in the majority of the patients. There have been some significant changes in the way we approach hodgkin lymphoma, especially in the early stages, in trying to prevent long term complications from treatments. Read more...

What cure is for hodgkin lymphoma?

Chemotherapy. Hodgkins disease is one of the malignant diseases that are highly curable. Most patients respond well to standard chemotherapy, small percentage need a second type if chemotherapy and some may need bone marrow rransplantaion. Read more...
While treatment. His highly successful, perhaps >90%, it is dependent on stage, bulk, cell type, age, and b symptoms (fever, soaking sweats, weight loss). Multi agent chemotherapy may be sufficient, but intelligent field, lower dose radiotherapy is added to areas of bulk. Marrow/stem cell used at relapse. Read more...

How accurate is the testing for hodgkin lymphoma?

Pathology. The best testing for hodgkins lymphoma is pathology reading, which means taking a biopsy from the lymph node and bone marrow, slides prepared and read under microscope by an expert pathologist. It is rare for an expert pathologist to misdiagnose a hodgkins lymphoma. Definitely after diagnosis a complete radiologic work up is needed to establish the stage. Read more...

What is a good way to check if I have hodgkin lymphoma?

You need your doctor. You can't. You should go to see your doctor and get further evaluation. Hodgkin's usually is presented with persistent significant swollen lymph nodes. In more advance case- also presented with abnormal low blood counts- when bone marrow is involved. Systemic symptoms like unexplained fever, chils, night sweats, significant weight loss can occur. Blood work , pet/ct scan and bone marrow biopsy needed. Read more...

How can I tell if I have hodgkin lymphoma? Cant stop thinking about it.

Are you a medical. Student? Hd is not common, usually presents with a lump in a nodal bearing area, but liver, spleen or mediastinal/hilar chest nodes can cause bulk symptoms there. Fever, soaking night sweats, weight loss are called "b" symptoms. A doctor can do a physical exam and discern fro your story whether the imaging is needed and what blood tests (cbc, sed rate, serum copper, liver enzymes, bili)) to do. Read more...

Can hodgkin lymphoma transform to NHL? After 4 cycle of ABVD, PET showed an area with SUV 14. Initial diagnosis was HL IIb, bulky.

Yes it can. This change has been reported, so it is entirely possible. But only a biopsy of the new area or the growing lymph node can determine what is going on. Your oncologist should be able to help address this matter for you. Or you can seek a second opinion from another medical oncologist, if you are not totally satisfied with your current oncologist. Read more...

What are some names of chemo that treat hodgkin lymphoma?

Many. There are many different regimens - some more common than others. Here is some additional info on the topic: http://www.Cancer.Net/cancer-types/lymphoma-hodgkin/treatment. Read more...
Many. Abvd (adriamycin, (doxorubicin) bleomycin, vinblastine 6 dacarbazine); stanford v (nitrogen mustard , adriamycin, (doxorubicin) vinblastine, vincristine, bleomycin etoposide, Prednisone ); beacopp (bleomycin, etoposide, adriamycin, (doxorubicin) cyclophosphamide, vincristine, Procarbazine prednisone); brentuximab vedotin; gemcitabine-navelbine. Read more...

Hodgkin lymphoma cancer--is it fatal?

Can be. Early statges of hodkin lymphoma are often curable. The prognosis depends on the type of disease and how widespread it may be at the time of diagnosis. Read more...