Exopthalmos. Associated with graves disease or hyperthyroidism is thought related to autoimmune process behind eyes.
Common antigen. The infiltrative exophthalmos that is frequently encountered, has been explained by postulating that the thyroid gland and the extraocular muscles share a common antigen that is recognized by the antibodies. Antibodies binding to the extraocular muscles would cause swelling behind the eyeball. This swelling has also been postulated to be the consequence of mucopolysacharide deposition posterior to.
High thyroid hormone. Graves Disease is an autoimmune disease that causes high levels of thyroid hormone. In addition to causing thyroid levels to elevate, Graves Disease causes an inflammatory process of the orbital tissues, predominantly affecting the fat and the extra ocular muscles however the deposition of glycosaminoglycans and the influx of water increase the orbital contents causing the eyes to bulge. Read more...