5 doctors weighed in:

Can I have celiac if a skin test was negative for wheat allergy?

5 doctors weighed in
Dr. Martin Ostro
Internal Medicine - Allergy & Immunology
4 doctors agree

In brief: Yes

Celiac is due to an immune reaction to certain components of wheat protein, gluten/gliadin, but is not due to allergic antibody (ige) to wheat, so skin testing is negative in celiac.
Certain blood tests showing immune reactions to certain intestinal enzymes, e.g. Tissue transglutaminase (ttg), are positive in celiac disease. Consult a gastroenterologist.

In brief: Yes

Celiac is due to an immune reaction to certain components of wheat protein, gluten/gliadin, but is not due to allergic antibody (ige) to wheat, so skin testing is negative in celiac.
Certain blood tests showing immune reactions to certain intestinal enzymes, e.g. Tissue transglutaminase (ttg), are positive in celiac disease. Consult a gastroenterologist.
Dr. Martin Ostro
Dr. Martin Ostro
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