6 doctors weighed in:
Is it normal for someone just told they had MS to be put on tysabri (natalizumab) before other treatment?
6 doctors weighed in

3 doctors agree
In brief: My opinion
Tysabri (natalizumab) has an FDA indication for first line use, and if a patient has quite active MS, I believe it is foolhardy to use less effective medications to start and then scale up after damage has become permanent.
The first 5 yrs seem most critical in the quest to stabilize MS.

In brief: My opinion
Tysabri (natalizumab) has an FDA indication for first line use, and if a patient has quite active MS, I believe it is foolhardy to use less effective medications to start and then scale up after damage has become permanent.
The first 5 yrs seem most critical in the quest to stabilize MS.
Dr. Bennett Machanic
Dr. Bennett Machanic
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1 comment
Dr. Mark Fisher
General acceptance of Tysabri as 1st-line DMT is quite recent, only within the last couple of years. Despite manufacturers' claims, I find all the other DMTs to be roughly the same in efficacy; differences are mainly in tolerability. Not everyone on Tysabri does spectacularly, but it does seem to me to bring about stabilization or actual improvement when nothing else has had much effect.
Dr. Horacio Capote
Psychiatry
1 doctor agrees
In brief: Can Be
Depends on the individual's particular circumstances.
Tysabri (natalizumab) can actually eliminate MS lesions in the central nervous system.

In brief: Can Be
Depends on the individual's particular circumstances.
Tysabri (natalizumab) can actually eliminate MS lesions in the central nervous system.
Dr. Horacio Capote
Dr. Horacio Capote
Thank
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