8 doctors weighed in:
If you have only the sickle cell trait, can you sometimes suffer like a person who has the disease?
8 doctors weighed in

Dr. Susumu Inoue
Pediatrics - Hematology & Oncology
4 doctors agree
In brief: On rare occasions
People with sickle cell trait under normal conditions (climate, altitude, normal life style) do not have any symptoms of sicle cell disease.
Very occasionally individulas who had severe stressful conditions (boot camp under extreme heat and with dehydration), or worked under significanly reduced oxygen pressure (high altitude) did experieince vaso-occulsive crisis. Or had sudden death.

In brief: On rare occasions
People with sickle cell trait under normal conditions (climate, altitude, normal life style) do not have any symptoms of sicle cell disease.
Very occasionally individulas who had severe stressful conditions (boot camp under extreme heat and with dehydration), or worked under significanly reduced oxygen pressure (high altitude) did experieince vaso-occulsive crisis. Or had sudden death.
Dr. Susumu Inoue
Dr. Susumu Inoue
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Dr. Kelty Baker
Internal Medicine - Hematology
2 doctors agree
In brief: Sickle cell trait
Sickle cell trait shouldn't cause pain crises like someone with the disease.
Sometimes patients are told they have trait but actually have sickle + thalassemia. Trait can cause problems however such as inability to concentrate the urine (isosthenuria), blood in the urine (renal papillary necrosis), kidney cancer, and sudden death if the patient gets dehydrated during vigorous physical exertion.

In brief: Sickle cell trait
Sickle cell trait shouldn't cause pain crises like someone with the disease.
Sometimes patients are told they have trait but actually have sickle + thalassemia. Trait can cause problems however such as inability to concentrate the urine (isosthenuria), blood in the urine (renal papillary necrosis), kidney cancer, and sudden death if the patient gets dehydrated during vigorous physical exertion.
Dr. Kelty Baker
Dr. Kelty Baker
Thank
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