How long can one take Estrace (estradiol) 1mg/day? Had Hysterectomy w/bilat oophorectomy- age 26 and started it then and now I'm 51.

Estrace (estradiol) Take this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Long-term estradiol treatment may increase your risk of breast cancer, ovarian cancer, or uterine cancer. Talk with your doctor about your individual risks before using estradiol long-term.