2 doctors weighed in:

Could a reaction to OTC nasal decongestant spray mimic a cluster headache?

2 doctors weighed in
1 doctor agrees

In brief: Maybe

There is no solid scientific data to support the direct cause and effect notion of phenyephrine/oxymetazoline decongestant nasal sprays mimicing cluster headaches.
Some link triggers to seasonal changes (fall/spring) or alcohol or extreme variations in body temperatures. The nasal decongestant association may have anecdotal support in certain individuals, but i haven't heard about it.

In brief: Maybe

There is no solid scientific data to support the direct cause and effect notion of phenyephrine/oxymetazoline decongestant nasal sprays mimicing cluster headaches.
Some link triggers to seasonal changes (fall/spring) or alcohol or extreme variations in body temperatures. The nasal decongestant association may have anecdotal support in certain individuals, but i haven't heard about it.
Dr. Michael H. T. Sia
Dr. Michael H. T. Sia
Thank
Get help from a real doctor now
Dr. Bennett Machanic
Board Certified, Neurology
48 years in practice
55M people helped
Continue
108,000 doctors available
Read more answers from doctors