Multiple myloma specialist needed pls help me confusing reports low m spike below 1 no crab but 14 percent plasma cells in Bone marrow biopsy worried?

Might be myeloma. Your plasma cells >10% in the bone marrow biopsy mean either smoldering myeloma or active myeloma. If you have elevated calcium, anemia, renal insufficiency or lytic bone lesions, I'm sorry to say you have myeloma. If not, you have smoldering myeloma. Go to this link for more info: http://www.nccn.org/patients/guidelines/myeloma/index.html.

Related Questions

Multiple myloma specialist needed confusing reports no crab features low m spike below 1 but 14 percent plasma cells in bone marrow pls help me?

"Pre-myeloma" http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001609/ http://myeloma.org/ArticlePage.action?tabId=1&menuId=334&articleId=3462&aTab=-1 http://myeloma.org/ArticlePage.action?tabId=1&menuId=334&articleId=3467&aTab=-1 Sorry I am not an oncologist. I will try to find one for you. Read more...

Can there be different opinion on beta 2 microglobulin and bone marrow biopsy regarding detection on multiple myeloma?

Probably not. The presence of more than 10% plasma cells in the bone marrow is supportive of the diagnosis. Once the diagnosis is confirmed the level of b2m is very important in terms of prognosis. Read more...
Beta 2 Microglobulin. Is a way of following myeloma response to therapy. The problem is that it can be elevated in other conditions- including benign ones. I've seen it very high in patients with kidney dysfunction. So the leel could be different than the bone marrow, which is the only real way to prove multiple myeloma. Read more...

I am wondering with normal SPEP, Bone marrow Biopsy, PET Scan All normal, high B2M is there chances for Myeloma or Waldenström's macroglobulinemia?

Yes. There is no test that will completely exclude nay diagnosis. In additon, b2m is a marker for all lymphoid disease (CLL, NHL, Hodgkin etc..) In any event, with the above negatvie studies the chances of you having lymphoma/myeloma missed is excedingly small. Read more...