Phemphigus vulgaris is a potentially fatal autoimmune mucocutaneous blistering disease.
Conventional therapy consists of high-dose corticosteroids, imminosuppressove agents, and intravenous immune globulin. Studies show that the biologic Rituximab and intravenous Immune Globulin is very effective with refractory pemphigus vulgaris. Mestinon (pyridostigmine) is not as effective as rituximab.
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