3 doctors weighed in:
What is the difference between pernicious anemia and megaloblastic anemia?
3 doctors weighed in

Dr. Liawaty Ho
Internal Medicine - Hematology & Oncology
2 doctors agree
In brief: Big RBC
Pernicious anemia is deficiency of vitaminb12 due to autoimmune attack on cell of the stomach and antibody against intrinsic factor- presented with megaloblastic anemia.
Pa is only one of the causes of megaloblastic anemia- however other causes that can cause def vitb12 , or folate (folic acid) or other drug eg. Bactrim- that inhibits dna synthesis in RBC production also can cause megaloblastic anemia.

In brief: Big RBC
Pernicious anemia is deficiency of vitaminb12 due to autoimmune attack on cell of the stomach and antibody against intrinsic factor- presented with megaloblastic anemia.
Pa is only one of the causes of megaloblastic anemia- however other causes that can cause def vitb12 , or folate (folic acid) or other drug eg. Bactrim- that inhibits dna synthesis in RBC production also can cause megaloblastic anemia.
Dr. Liawaty Ho
Dr. Liawaty Ho
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